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The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease with high mortality. Treatments, which can result in significant morbidity, have not substantially changed in three decades. The second messenger cyclic GMP (cGMP), which targets protein kinase G (PKG), is generated by guanylate...

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Dettagli Bibliografici
Pubblicato in:Cancer Lett
Autori principali: Tuttle, Traci R., Mierzwa, Michelle L., Wells, Susanne I., Fox, Sejal R., Ben-Jonathan, Nira
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711273/
https://ncbi.nlm.nih.gov/pubmed/26551887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.10.024
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