CYCLIC GMP/PROTEIN KINASE G CONTROL A SRC-CONTAINING MECHANOSOME IN OSTEOBLASTS

Mechanical stimulation is crucial for bone growth/remodeling, and fluid shear stress promotes anabolic responses in osteoblasts through multiple second messengers, including nitric oxide (NO), but the underlying mechanisms are not well understood. Here we demonstrate that the NO/cGMP/PKG signaling p...

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Detalhes bibliográficos
Main Authors: Rangaswami, Hema, Schwappacher, Raphaela, Marathe, Nisha, Zhuang, Shunhui, Casteel, Darren E., Haas, Bodo, Chen, Yong, Pfeifer, Alexander, Kato, Hisashi, Shattil, Sanford, Boss, Gerry R., Pilz, Renate B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093297/
https://ncbi.nlm.nih.gov/pubmed/21177494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001423
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