CYCLIC GMP/PROTEIN KINASE G CONTROL A SRC-CONTAINING MECHANOSOME IN OSTEOBLASTS

Mechanical stimulation is crucial for bone growth/remodeling, and fluid shear stress promotes anabolic responses in osteoblasts through multiple second messengers, including nitric oxide (NO), but the underlying mechanisms are not well understood. Here we demonstrate that the NO/cGMP/PKG signaling p...

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Main Authors: Rangaswami, Hema, Schwappacher, Raphaela, Marathe, Nisha, Zhuang, Shunhui, Casteel, Darren E., Haas, Bodo, Chen, Yong, Pfeifer, Alexander, Kato, Hisashi, Shattil, Sanford, Boss, Gerry R., Pilz, Renate B.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093297/
https://ncbi.nlm.nih.gov/pubmed/21177494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001423
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