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The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease with high mortality. Treatments, which can result in significant morbidity, have not substantially changed in three decades. The second messenger cyclic GMP (cGMP), which targets protein kinase G (PKG), is generated by guanylate...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Tuttle, Traci R., Mierzwa, Michelle L., Wells, Susanne I., Fox, Sejal R., Ben-Jonathan, Nira
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711273/
https://ncbi.nlm.nih.gov/pubmed/26551887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.10.024
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