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The cyclic GMP/protein kinase G pathway as a therapeutic target in head and neck squamous cell carcinoma

Head and neck squamous cell carcinoma (HNSCC) is an aggressive disease with high mortality. Treatments, which can result in significant morbidity, have not substantially changed in three decades. The second messenger cyclic GMP (cGMP), which targets protein kinase G (PKG), is generated by guanylate...

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Publicat a:Cancer Lett
Autors principals: Tuttle, Traci R., Mierzwa, Michelle L., Wells, Susanne I., Fox, Sejal R., Ben-Jonathan, Nira
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711273/
https://ncbi.nlm.nih.gov/pubmed/26551887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2015.10.024
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