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Soluble guanylate cyclase stimulators increase sensitivity to cisplatin in head and neck squamous cell carcinoma cells

Head and neck squamous cell carcinoma (HNSCC) is an aggressive and often fatal disease. Cisplatin is the most common chemotherapeutic drug in the treatment of HNSCC, but intrinsic and acquired resistance are frequent, and severe side effects occur at high doses. The second messenger cyclic GMP (cGMP...

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Bibliografiske detaljer
Udgivet i:Cancer Lett
Main Authors: Tuttle, Traci R., Takiar, Vinita, Kumar, Bhavna, Kumar, Pawan, Ben-Jonathan, Nira
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313285/
https://ncbi.nlm.nih.gov/pubmed/28025101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.12.020
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