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Decitabine Rescues Cisplatin Resistance in Head and Neck Squamous Cell Carcinoma
Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC) reduces survival. In this study we hypothesized that methylation of key genes mediates cisplatin resistance. We determined whether a demethylating drug, decitabine, could augment the anti-proliferative and apoptotic effects of cis...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229295/ https://ncbi.nlm.nih.gov/pubmed/25391133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112880 |
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