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Decitabine Rescues Cisplatin Resistance in Head and Neck Squamous Cell Carcinoma
Cisplatin resistance in head and neck squamous cell carcinoma (HNSCC) reduces survival. In this study we hypothesized that methylation of key genes mediates cisplatin resistance. We determined whether a demethylating drug, decitabine, could augment the anti-proliferative and apoptotic effects of cis...
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| Publicado en: | PLoS One |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4229295/ https://ncbi.nlm.nih.gov/pubmed/25391133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112880 |
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