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A quantitative understanding of lac repressor’s binding specificity and flexibility

Lac repressor, the first discovered transcriptional regulator, has been shown to confer multiple-modes of binding to its operator sites depending on the central spacer length. Other homolog members in the LacI/GalR family (PurR and YcjW) cannot bind their operator sites with similar structural flexi...

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Bibliografiske detaljer
Udgivet i:Quant Biol
Main Authors: Zuo, Zheng, Chang, Yiming, Stormo, Gary D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4704127/
https://ncbi.nlm.nih.gov/pubmed/26752632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40484-015-0044-z
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