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Quantitative modeling of DNA–protein interactions: effects of amino acid substitutions on binding specificity of the Mnt repressor
Understanding DNA–protein recognition quantitatively is essential to developing computational algorithms for accurate transcriptional binding site prediction. Using a quantitative, multiple fluorescence, relative affinity (QuMFRA) assay, we determine the binding specificity of 11 different position...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC506813/ https://ncbi.nlm.nih.gov/pubmed/15289576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh729 |
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