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Specificity of Mnt ‘master residue’ obtained from in vivo and in vitro selections

Mnt is a repressor from phage P22 that belongs to the ribbon–helix–helix family of DNA binding factors. Four amino acids from the N-terminus of the protein, Arg2, His6, Asn8 and Arg10, interact with the base pairs of the DNA to provide the sequence specificity. Raumann et al. (Nature Struct. Biol.,...

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Autors principals: Silbaq, Fauzi S., Ruttenberg, Steven E., Stormo, Gary D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC140065/
https://ncbi.nlm.nih.gov/pubmed/12490722
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