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Measuring quantitative effects of methylation on transcription factor–DNA binding affinity
Methylation of CpG (cytosine-phosphate-guanine) dinucleotides is a common epigenetic mark that influences gene expression. The effects of methylation on transcription factor (TF) binding are unknown for most TFs and, even when known, such knowledge is often only qualitative. In reality, methylation...
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| Gepubliceerd in: | Sci Adv |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Association for the Advancement of Science
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5694663/ https://ncbi.nlm.nih.gov/pubmed/29159284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aao1799 |
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