Integrated microfluidic approach for quantitative high-throughput measurements of transcription factor binding affinities

Protein binding to DNA is a fundamental process in gene regulation. Methodologies such as ChIP-Seq and mapping of DNase I hypersensitive sites provide global information on this regulation in vivo. In vitro methodologies provide valuable complementary information on protein–DNA specificities. Howeve...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Glick, Yair, Orenstein, Yaron, Chen, Dana, Avrahami, Dorit, Zor, Tsaffrir, Shamir, Ron, Gerber, Doron
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824076/
https://ncbi.nlm.nih.gov/pubmed/26635393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1327
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