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High-Resolution Specificity from DNA Sequencing Highlights Alternative Modes of Lac Repressor Binding

Knowing the specificity of transcription factors is critical to understanding regulatory networks in cells. The lac repressor–operator system has been studied for many years, but not with high-throughput methods capable of determining specificity comprehensively. Details of its binding interaction a...

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Detalles Bibliográficos
Publicado en:Genetics
Main Authors: Zuo, Zheng, Stormo, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224169/
https://ncbi.nlm.nih.gov/pubmed/25209146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.170100
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