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High-Resolution Specificity from DNA Sequencing Highlights Alternative Modes of Lac Repressor Binding

Knowing the specificity of transcription factors is critical to understanding regulatory networks in cells. The lac repressor–operator system has been studied for many years, but not with high-throughput methods capable of determining specificity comprehensively. Details of its binding interaction a...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Zuo, Zheng, Stormo, Gary D.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224169/
https://ncbi.nlm.nih.gov/pubmed/25209146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.170100
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