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Comparison of the super agonist complex, ALT-803, to IL-15 as cancer immunotherapeutics in animal models
Interleukin-15 (IL-15), a potent stimulant of CD8(+) T and NK cells, is a promising cancer immunotherapeutic. ALT-803 is a complex of an IL-15 superagonist mutant and a dimeric IL-15 receptor αSu/Fc fusion protein that was found to exhibit enhanced biologic activity in vivo with a substantially long...
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| 出版年: | Cancer Immunol Res |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4703482/ https://ncbi.nlm.nih.gov/pubmed/26511282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-15-0093-T |
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