SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response

Chronic lymphocytic leukemia (CLL) is a variable disease; therefore, markers to identify aggressive forms are essential for patient management. Here, we have shown that expression of the costimulatory molecule and microbial sensor SLAMF1 (also known as CD150) is lost in a subset of patients with an...

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Publicat a:J Clin Invest
Autors principals: Bologna, Cinzia, Buonincontri, Roberta, Serra, Sara, Vaisitti, Tiziana, Audrito, Valentina, Brusa, Davide, Pagnani, Andrea, Coscia, Marta, D’Arena, Giovanni, Mereu, Elisabetta, Piva, Roberto, Furman, Richard R., Rossi, Davide, Gaidano, Gianluca, Terhorst, Cox, Deaglio, Silvia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701571/
https://ncbi.nlm.nih.gov/pubmed/26619119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83013
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