HLA-G is a component of the chronic lymphocytic leukemia escape repertoire to generate immune suppression: impact of the HLA-G 14 base pair (rs66554220) polymorphism

This work investigates the possibility that HLA-G, a molecule modulating innate and adaptive immunity, is part of an immune escape strategy of chronic lymphocytic leukemia cells. A 14 base pair insertion/deletion polymorphism (rs66554220) in the 3′-untranslated region of HLA-G influences mRNA stabil...

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Hlavní autoři: Rizzo, Roberta, Audrito, Valentina, Vacca, Paola, Rossi, Davide, Brusa, Davide, Stignani, Marina, Bortolotti, Daria, D’Arena, Giovanni, Coscia, Marta, Laurenti, Luca, Forconi, Francesco, Gaidano, Gianluca, Mingari, Maria Cristina, Moretta, Lorenzo, Malavasi, Fabio, Deaglio, Silvia
Médium: Artigo
Jazyk:Inglês
Vydáno: Ferrata Storti Foundation 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008099/
https://ncbi.nlm.nih.gov/pubmed/24362551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2013.095281
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