Inhibitory receptors sensing HLA-G1 molecules in pregnancy: Decidua-associated natural killer cells express LIR-1 and CD94/NKG2A and acquire p49, an HLA-G1-specific receptor

Trophoblastic cells lack classical HLA class I and class II molecules but express HLA-G1. Although this may prevent allorecognition by maternal T cells, it renders trophoblastic cells potentially susceptible to lysis by natural killer (NK) cells. As shown here, only a fraction of peripheral-blood NK...

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Detalhes bibliográficos
Main Authors: Ponte, Marco, Cantoni, Claudia, Biassoni, Roberto, Tradori-Cappai, Andrea, Bentivoglio, Giorgio, Vitale, Chiara, Bertone, Stefania, Moretta, Alessandro, Moretta, Lorenzo, Mingari, Maria Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC21919/
https://ncbi.nlm.nih.gov/pubmed/10318943
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