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SLAMF1 regulation of chemotaxis and autophagy determines CLL patient response

Chronic lymphocytic leukemia (CLL) is a variable disease; therefore, markers to identify aggressive forms are essential for patient management. Here, we have shown that expression of the costimulatory molecule and microbial sensor SLAMF1 (also known as CD150) is lost in a subset of patients with an...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Bologna, Cinzia, Buonincontri, Roberta, Serra, Sara, Vaisitti, Tiziana, Audrito, Valentina, Brusa, Davide, Pagnani, Andrea, Coscia, Marta, D’Arena, Giovanni, Mereu, Elisabetta, Piva, Roberto, Furman, Richard R., Rossi, Davide, Gaidano, Gianluca, Terhorst, Cox, Deaglio, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701571/
https://ncbi.nlm.nih.gov/pubmed/26619119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83013
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