Adenosine signaling mediates hypoxic responses in the chronic lymphocytic leukemia microenvironment

The chronic lymphocytic leukemia (CLL) niche is a closed environment where leukemic cells derive growth and survival signals through their interaction with macrophages and T lymphocytes. Here, we show that the CLL lymph node niche is characterized by overexpression and activation of HIF-1α, which in...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Blood Adv
Main Authors: Serra, Sara, Vaisitti, Tiziana, Audrito, Valentina, Bologna, Cinzia, Buonincontri, Roberta, Chen, Shih-Shih, Arruga, Francesca, Brusa, Davide, Coscia, Marta, Jaksic, Ozren, Inghirami, Giorgio, Rossi, Davide, Furman, Richard R., Robson, Simon C., Gaidano, Gianluca, Chiorazzi, Nicholas, Deaglio, Silvia
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2016
Fag:
Lymphoid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744057/
https://ncbi.nlm.nih.gov/pubmed/29296695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016000984
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker