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Pore Structure and Synergy in Antimicrobial Peptides of the Magainin Family

Magainin 2 and PGLa are among the best-studied cationic antimicrobial peptides. They bind preferentially to negatively charged membranes and apparently cause their disruption by the formation of transmembrane pores, whose detailed structure is still unclear. Here we report the results of 5–9 μs all-...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Pino-Angeles, Almudena, Leveritt, John M., Lazaridis, Themis
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699650/
https://ncbi.nlm.nih.gov/pubmed/26727376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004570
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