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Pore Structure and Synergy in Antimicrobial Peptides of the Magainin Family

Magainin 2 and PGLa are among the best-studied cationic antimicrobial peptides. They bind preferentially to negatively charged membranes and apparently cause their disruption by the formation of transmembrane pores, whose detailed structure is still unclear. Here we report the results of 5–9 μs all-...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Pino-Angeles, Almudena, Leveritt, John M., Lazaridis, Themis
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699650/
https://ncbi.nlm.nih.gov/pubmed/26727376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004570
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