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Effects of Peptide Charge, Orientation, and Concentration on Melittin Transmembrane Pores

Melittin is a short cationic peptide that exerts cytolytic effects on bacterial and eukaryotic cells. Experiments suggest that in zwitterionic membranes, melittin forms transmembrane toroidal pores supported by four to eight peptides. A recently constructed melittin variant with a reduced cationic c...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Pino-Angeles, Almudena, Lazaridis, Themis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026367/
https://ncbi.nlm.nih.gov/pubmed/29925023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.05.006
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