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Effects of Peptide Charge, Orientation, and Concentration on Melittin Transmembrane Pores
Melittin is a short cationic peptide that exerts cytolytic effects on bacterial and eukaryotic cells. Experiments suggest that in zwitterionic membranes, melittin forms transmembrane toroidal pores supported by four to eight peptides. A recently constructed melittin variant with a reduced cationic c...
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| Udgivet i: | Biophys J |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6026367/ https://ncbi.nlm.nih.gov/pubmed/29925023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.05.006 |
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