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Antimicrobial peptides bind more strongly to membrane pores

Antimicrobial peptides (AMPs) are small, usually cationic peptides, which permeabilize bacterial membranes. Understanding their mechanism of action might help design better antibiotics. Using an implicit membrane model, modified to include pores of different shapes, we show that four AMPs (alamethic...

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Main Authors: Mihajlovic, Maja, Lazaridis, Themis
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885479/
https://ncbi.nlm.nih.gov/pubmed/20188066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.02.023
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