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Antimicrobial peptides bind more strongly to membrane pores

Antimicrobial peptides (AMPs) are small, usually cationic peptides, which permeabilize bacterial membranes. Understanding their mechanism of action might help design better antibiotics. Using an implicit membrane model, modified to include pores of different shapes, we show that four AMPs (alamethic...

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Bibliografiska uppgifter
Huvudupphovsmän: Mihajlovic, Maja, Lazaridis, Themis
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885479/
https://ncbi.nlm.nih.gov/pubmed/20188066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.02.023
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