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Antimicrobial peptides bind more strongly to membrane pores

Antimicrobial peptides (AMPs) are small, usually cationic peptides, which permeabilize bacterial membranes. Understanding their mechanism of action might help design better antibiotics. Using an implicit membrane model, modified to include pores of different shapes, we show that four AMPs (alamethic...

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Autors principals: Mihajlovic, Maja, Lazaridis, Themis
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885479/
https://ncbi.nlm.nih.gov/pubmed/20188066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.02.023
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