Nalaganje...

How do mutations thermostabilize G protein-coupled receptors?

Structures of over 30 different G protein-coupled receptors (GPCRs) have advanced our understanding of cell signaling and provided a foundation for structure-guided drug design. This exciting progress required the development of three complimentary methods to facilitate GPCR crystallization, one of...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Trends Pharmacol Sci
Main Authors: Vaidehi, Nagarajan, Grisshammer, Reinhard, Tate, Christopher G.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698185/
https://ncbi.nlm.nih.gov/pubmed/26547284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2015.09.005
Oznake: Označite
Brez oznak, prvi označite!