Metal-specific CD4(+) T cell responses induced by beryllium exposure in HLA-DP2 transgenic mice

Chronic beryllium disease (CBD) is a granulomatous lung disorder that is associated with the accumulation of beryllium (Be)-specific CD4(+) T cells into the lung. Genetic susceptibility is linked to HLA-DPB1 alleles that possess a glutamic acid at position 69 (βGlu69), and HLA-DPB1*02:01 is the most...

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Publicado no:Mucosal Immunol
Main Authors: Falta, Michael T., Tinega, Alex N., Mack, Douglas G., Bowerman, Natalie A., Crawford, Frances, Kappler, John W., Pinilla, Clemencia, Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698108/
https://ncbi.nlm.nih.gov/pubmed/26129650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.54
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