Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease

Susceptibility to chronic beryllium disease (CBD) is linked to certain HLA-DP molecules, including HLA-DP2. To elucidate the molecular basis of this association, we exposed mice transgenic (Tg) for HLA-DP2 to beryllium oxide (BeO) via oropharyngeal aspiration. As opposed to WT mice, BeO-exposed HLA-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mack, Douglas G., Falta, Michael T., McKee, Amy S., Martin, Allison K., Simonian, Philip L., Crawford, Frances, Gordon, Terry, Mercer, Robert R., Hoover, Mark D., Marrack, Philippa, Kappler, John W., Tuder, Rubin M., Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060652/
https://ncbi.nlm.nih.gov/pubmed/24912188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408048111
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados