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Crystal structure of HLA-DP2 and implications for chronic beryllium disease

Chronic beryllium disease (CBD) is a fibrotic lung disorder caused by beryllium (Be) exposure and is characterized by granulomatous inflammation and the accumulation of Be-responsive CD4(+) T cells in the lung. Genetic susceptibility to CBD has been associated with certain alleles of the MHCII molec...

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Detalhes bibliográficos
Main Authors: Dai, Shaodong, Murphy, Guinevere A., Crawford, Frances, Mack, Douglas G., Falta, Michael T., Marrack, Philippa, Kappler, John W., Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867715/
https://ncbi.nlm.nih.gov/pubmed/20356827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001772107
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