Structural Basis of Chronic Beryllium Disease: Linking Allergic Hypersensitivity and Autoimmunity

T cell-mediated hypersensitivity to metal cations is common in humans. How the T cell antigen receptor (TCR) recognizes these cations bound to a major histocompatibility complex (MHC) protein and self-peptide is unknown. Individuals carrying the MHCII allele, HLA-DP2, are at risk for chronic berylli...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Clayton, Gina M., Wang, Yang, Crawford, Frances, Novikov, Andrey, Wimberly, Brian T., Kieft, Jeffrey S., Falta, Michael T., Bowerman, Natalie A., Marrack, Philippa, Fontenot, Andrew P., Dai, Shaodong, Kappler, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269484/
https://ncbi.nlm.nih.gov/pubmed/24995984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.048
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