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Structural Basis of Chronic Beryllium Disease: Linking Allergic Hypersensitivity and Autoimmunity
T cell-mediated hypersensitivity to metal cations is common in humans. How the T cell antigen receptor (TCR) recognizes these cations bound to a major histocompatibility complex (MHC) protein and self-peptide is unknown. Individuals carrying the MHCII allele, HLA-DP2, are at risk for chronic berylli...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4269484/ https://ncbi.nlm.nih.gov/pubmed/24995984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.048 |
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