Linking Genetic Susceptibility and T Cell Activation in Beryllium-induced Disease

Chronic beryllium disease (CBD) is a granulomatous lung disorder caused by beryllium (Be) exposure in the workplace. It is characterized by the accumulation of Be-specific CD4(+) T cells in the lung as well as persistent lung inflammation, culminating in the development of lung fibrosis. CBD occurs...

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Detalhes bibliográficos
Main Authors: Falta, Michael T., Bowerman, Natalie A., Dai, Shaodong, Kappler, John W., Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
THOMAS L. PETTY ASPEN LUNG CONFERENCE: The Environment and the Lung: Detection, Prevention, and Mechanisms of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266018/
https://ncbi.nlm.nih.gov/pubmed/20427584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201002-022RM
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