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Mutagenesis of beryllium-specific T cell receptors suggests an unusual binding topology for antigen recognition
Unconventional antigens, such as metals, stimulate T cells in a very specific manner. To delineate the binding landscape for metal-specific T cell recognition, alanine screens were performed on a set of beryllium (Be)-specific T cell receptors (TCR) derived from the lung of a chronic beryllium disea...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3178675/ https://ncbi.nlm.nih.gov/pubmed/21873524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101872 |
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