Identification of beryllium-dependent peptides recognized by CD4(+) T cells in chronic beryllium disease

Chronic beryllium disease (CBD) is a granulomatous disorder characterized by an influx of beryllium (Be)-specific CD4(+) T cells into the lung. The vast majority of these T cells recognize Be in an HLA-DP–restricted manner, and peptide is required for T cell recognition. However, the peptides that s...

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Detalhes bibliográficos
Main Authors: Falta, Michael T., Pinilla, Clemencia, Mack, Douglas G., Tinega, Alex N., Crawford, Frances, Giulianotti, Marc, Santos, Radleigh, Clayton, Gina M., Wang, Yuxiao, Zhang, Xuewu, Maier, Lisa A., Marrack, Philippa, Kappler, John W., Fontenot, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3698527/
https://ncbi.nlm.nih.gov/pubmed/23797096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122426
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