Structural Basis of Chronic Beryllium Disease: Linking Allergic Hypersensitivity and Autoimmunity

T cell-mediated hypersensitivity to metal cations is common in humans. How the T cell antigen receptor (TCR) recognizes these cations bound to a major histocompatibility complex (MHC) protein and self-peptide is unknown. Individuals carrying the MHCII allele, HLA-DP2, are at risk for chronic berylli...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Clayton, Gina M., Wang, Yang, Crawford, Frances, Novikov, Andrey, Wimberly, Brian T., Kieft, Jeffrey S., Falta, Michael T., Bowerman, Natalie A., Marrack, Philippa, Fontenot, Andrew P., Dai, Shaodong, Kappler, John W.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269484/
https://ncbi.nlm.nih.gov/pubmed/24995984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.048
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