Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR). However, the role of ER stress in tumor initiation and progression is controversial. To determine the impact of ER stress,...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Paridaens, Annelies, Bogaerts, Eliene, Verhelst, Xavier, Van den Bussche, Anja, Raevens, Sarah, Van Steenkiste, Christophe, Van Troys, Marleen, Ampe, Christophe, Descamps, Benedicte, Vanhove, Chris, Govaere, Olivier, Geerts, Anja, Van Vlierberghe, Hans
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695041/
https://ncbi.nlm.nih.gov/pubmed/26293671
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