Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. We previously showed that the inhibition of placental growth factor (PlGF) exerts antitumour effects and induces vessel normalisation, possibly reducing hypoxia. However, the exact mechanism underlying these e...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Bogaerts, Eliene, Paridaens, Annelies, Van den Bussche, Anja, Raevens, Sarah, Verhelst, Xavier, Van Steenkiste, Christophe, Jonckx, Bart, Libbrecht, Louis, Geerts, Anja, Carmeliet, Peter, Van Vlierberghe, Hans
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707726/
https://ncbi.nlm.nih.gov/pubmed/26753564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1990-6
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker