Placental growth factor inhibition modulates the interplay between hypoxia and unfolded protein response in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality. We previously showed that the inhibition of placental growth factor (PlGF) exerts antitumour effects and induces vessel normalisation, possibly reducing hypoxia. However, the exact mechanism underlying these e...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:BMC Cancer
Main Authors: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Bogaerts, Eliene, Paridaens, Annelies, Van den Bussche, Anja, Raevens, Sarah, Verhelst, Xavier, Van Steenkiste, Christophe, Jonckx, Bart, Libbrecht, Louis, Geerts, Anja, Carmeliet, Peter, Van Vlierberghe, Hans
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4707726/
https://ncbi.nlm.nih.gov/pubmed/26753564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1990-6
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares