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Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR). However, the role of ER stress in tumor initiation and progression is controversial. To determine the impact of ER stress,...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Paridaens, Annelies, Bogaerts, Eliene, Verhelst, Xavier, Van den Bussche, Anja, Raevens, Sarah, Van Steenkiste, Christophe, Van Troys, Marleen, Ampe, Christophe, Descamps, Benedicte, Vanhove, Chris, Govaere, Olivier, Geerts, Anja, Van Vlierberghe, Hans
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695041/
https://ncbi.nlm.nih.gov/pubmed/26293671
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