Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR). However, the role of ER stress in tumor initiation and progression is controversial. To determine the impact of ER stress,...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Paridaens, Annelies, Bogaerts, Eliene, Verhelst, Xavier, Van den Bussche, Anja, Raevens, Sarah, Van Steenkiste, Christophe, Van Troys, Marleen, Ampe, Christophe, Descamps, Benedicte, Vanhove, Chris, Govaere, Olivier, Geerts, Anja, Van Vlierberghe, Hans
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695041/
https://ncbi.nlm.nih.gov/pubmed/26293671
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