Tauroursodeoxycholic acid dampens oncogenic apoptosis induced by endoplasmic reticulum stress during hepatocarcinogen exposure

Hepatocellular carcinoma (HCC) is characterized by the accumulation of unfolded proteins in the endoplasmic reticulum (ER), which activates the unfolded protein response (UPR). However, the role of ER stress in tumor initiation and progression is controversial. To determine the impact of ER stress,...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Vandewynckel, Yves-Paul, Laukens, Debby, Devisscher, Lindsey, Paridaens, Annelies, Bogaerts, Eliene, Verhelst, Xavier, Van den Bussche, Anja, Raevens, Sarah, Van Steenkiste, Christophe, Van Troys, Marleen, Ampe, Christophe, Descamps, Benedicte, Vanhove, Chris, Govaere, Olivier, Geerts, Anja, Van Vlierberghe, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695041/
https://ncbi.nlm.nih.gov/pubmed/26293671
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