Anti–miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice

Fc receptor for IgG IIA (FcγRIIA)–mediated platelet activation is essential in heparin-induced thrombocytopenia (HIT) and other immune-mediated thrombocytopenia and thrombosis disorders. There is considerable interindividual variation in platelet FcγRIIA activation, the reasons for which remain uncl...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Zhou, Yuhang, Abraham, Shaji, Andre, Pierrette, Edelstein, Leonard C., Shaw, Chad A., Dangelmaier, Carol A., Tsygankov, Alexander Y., Kunapuli, Satya P., Bray, Paul F., McKenzie, Steven E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2015
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692146/
https://ncbi.nlm.nih.gov/pubmed/26516227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-631135
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