Rapid ubiquitination of Syk following GPVI activation in platelets

Spleen tyrosine kinase (Syk) activation is a key intermediate step in the activation of platelets by the physiologic agonist collagen. We have found that Syk is rapidly ubiquitinated upon activation of platelets by collagen, collagen-related peptide (CRP), and convulxin. The Src family kinase inhibi...

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Главные авторы: Dangelmaier, Carol A., Quinter, Patricia G., Jin, Jianguo, Tsygankov, Alexander Y., Kunapuli, Satya P., Daniel, James L.
Формат: Artigo
Язык:Inglês
Опубликовано: © 2005 by The American Society of Hematology 2005
Предметы:
Hemostasis, Thrombosis, and Vascular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895068/
https://ncbi.nlm.nih.gov/pubmed/15701717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3689
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