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Rapid ubiquitination of Syk following GPVI activation in platelets
Spleen tyrosine kinase (Syk) activation is a key intermediate step in the activation of platelets by the physiologic agonist collagen. We have found that Syk is rapidly ubiquitinated upon activation of platelets by collagen, collagen-related peptide (CRP), and convulxin. The Src family kinase inhibi...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
© 2005 by The American Society of Hematology
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895068/ https://ncbi.nlm.nih.gov/pubmed/15701717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2004-09-3689 |
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