A novel histidine tyrosine phosphatase, TULA-2, associates with Syk and negatively regulates GPVI signaling in platelets

T-cell ubiquitin ligand-2 (TULA-2) is a recently discovered histidine tyrosine phosphatase thought to be ubiquitously expressed. In this work, we have investigated whether TULA-2 has a key role in platelet glycoprotein VI (GPVI) signaling. This study indicates that TULA-2 is expressed in human and m...

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Main Authors: Thomas, Dafydd H., Getz, Todd M., Newman, Tiffanny N., Dangelmaier, Carol A., Carpino, Nick, Kunapuli, Satya P., Tsygankov, Alexander Y., Daniel, James L.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Platelets and Thrombopoiesis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953889/
https://ncbi.nlm.nih.gov/pubmed/20585042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-268136
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