Determination of the Substrate Specificity of Protein-tyrosine Phosphatase TULA-2 and Identification of Syk as a TULA-2 Substrate

TULA-1 (UBASH3A/STS-2) and TULA-2 (p70/STS-1) represent a novel class of protein-tyrosine phosphatases. Previous studies suggest that TULA-2 is sequence-selective toward phosphotyrosyl (Tyr(P)) peptides. In this work the substrate specificity of TULA-1 and -2 was systematically evaluated by screenin...

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Detalhes bibliográficos
Main Authors: Chen, Xianwen, Ren, Lige, Kim, Soochong, Carpino, Nicholas, Daniel, James L., Kunapuli, Satya P., Tsygankov, Alexander Y., Pei, Dehua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951201/
https://ncbi.nlm.nih.gov/pubmed/20670933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.114181
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