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Structural insights into the DNA-binding specificity of E2F family transcription factors
The mammalian cell cycle is controlled by the E2F family of transcription factors. Typical E2Fs bind to DNA as heterodimers with the related dimerization partner (DP) proteins, whereas the atypical E2Fs, E2F7 and E2F8 contain two DNA-binding domains (DBDs) and act as repressors. To understand the me...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4686757/ https://ncbi.nlm.nih.gov/pubmed/26632596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10050 |
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