Redox proteomics analysis of HNE-modified proteins in DS brain: clues for understanding development of Alzheimer disease

Down syndrome (DS) is the most common genetic cause of intellectual disability, due to partial or complete triplication of chromosome 21. DS subjects are characterized by a number of abnormalities including premature aging and development of Alzheimer’s disease (AD) neuropathology after approximatel...

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Publicado en:Free Radic Biol Med
Autores principales: Di Domenico, Fabio, Pupo, Gilda, Tramutola, Antonella, Giorgi, Alessandra, Schininà, Maria Eugenia, Coccia, Raffaella, Head, Elizabeth, Butterfield, D. Allan, Perluigi, Marzia
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686229/
https://ncbi.nlm.nih.gov/pubmed/24675226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.027
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