Redox proteomics analysis of HNE-modified proteins in DS brain: clues for understanding development of Alzheimer disease

Down syndrome (DS) is the most common genetic cause of intellectual disability, due to partial or complete triplication of chromosome 21. DS subjects are characterized by a number of abnormalities including premature aging and development of Alzheimer’s disease (AD) neuropathology after approximatel...

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Библиографические подробности
Опубликовано в: :Free Radic Biol Med
Главные авторы: Di Domenico, Fabio, Pupo, Gilda, Tramutola, Antonella, Giorgi, Alessandra, Schininà, Maria Eugenia, Coccia, Raffaella, Head, Elizabeth, Butterfield, D. Allan, Perluigi, Marzia
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686229/
https://ncbi.nlm.nih.gov/pubmed/24675226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.027
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