Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer’s disease neuropathology: Redox proteomics analysis of human brain

DS is the most frequent genetic cause of intellectual disability characterized by the anomalous presence of three copies of chromosome 21. One of the peculiar features of DS is the onset of Alzheimer’s disease neuropathology after the age of 40 years characterized by deposition of senile plaques and...

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Detaylı Bibliyografya
Asıl Yazarlar: Di Domenico, Fabio, Coccia, Raffaella, Cocciolo, Annalisa, Murphy, M. Paul, Cenini, Giovanna, Head, Elizabeth, Butterfield, D. Allan, Giorgi, Alessandra, Schinina, Maria Eugenia, Mancuso, Cesare, Cini, Chiara, Perluigi, Marzia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3940071/
https://ncbi.nlm.nih.gov/pubmed/23603808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2013.04.013
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