Redox proteomics identification of 4-hydroxynonenal-modified brain proteins in Alzheimer’s disease: Role of lipid peroxidation in Alzheimer’s disease pathogenesis

Numerous studies have shown that neuronal lipids are highly susceptible to oxidative stress including in those brain areas directly involved in the neurodegenerative process of Alzheimer’s disease (AD). Lipid peroxidation directly damages membranes and also generates a number of secondary biological...

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Autori principali: Perluigi, Marzia, Sultana, Rukhsana, Cenini, Giovanna, Di Domenico, Fabio, Memo, Maurizio, Pierce, William M., Coccia, Raffaella, Butterfield, D. Allan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843938/
https://ncbi.nlm.nih.gov/pubmed/20333275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.200800161
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