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Effects of Oxidative and Nitrosative Stress in Brain on p53 Pro-apoptotic Protein in Amnestic Mild Cognitive Impairment and Alzheimer Disease

Many studies reported that oxidative and nitrosative stress might be important for the pathogenesis of Alzheimer’s disease (AD) beginning with arguably the earliest stage of AD, i.e., as mild cognitive impairment (MCI). p53 is a pro-apoptotic protein that plays an important role in neuronal death, a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cenini, Giovanna, Sultana, Rukhsana, Memo, Maurizio, Butterfield, D. Allan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587421/
https://ncbi.nlm.nih.gov/pubmed/18439434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.03.015
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