Loss of Phospholipid Asymmetry and Elevated Brain Apoptotic Protein Levels in Subjects with Amnestic Mild Cognitive Impairment and Alzheimer Disease

Oxidative stress, a hallmark of Alzheimer disease (AD), has been shown to induce lipid peroxidation and apoptosis disrupting cellular homeostasis. Normally, the aminophospholipid phosphatidylserine (PtdSer) is asymmetrically distributed on the cytosolic leaflet of the lipid bilayer. Under oxidative...

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Main Authors: Bader Lange, Miranda L., Cenini, Giovanna, Piroddi, Marta, Abdul, Hafiz Mohmmad, Sultana, Rukhsana, Galli, Francesco, Memo, Maurizio, Butterfield, D. Allan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292396/
https://ncbi.nlm.nih.gov/pubmed/18077176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.11.004
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