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Loss of Phospholipid Asymmetry and Elevated Brain Apoptotic Protein Levels in Subjects with Amnestic Mild Cognitive Impairment and Alzheimer Disease

Oxidative stress, a hallmark of Alzheimer disease (AD), has been shown to induce lipid peroxidation and apoptosis disrupting cellular homeostasis. Normally, the aminophospholipid phosphatidylserine (PtdSer) is asymmetrically distributed on the cytosolic leaflet of the lipid bilayer. Under oxidative...

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Bibliografiske detaljer
Main Authors: Bader Lange, Miranda L., Cenini, Giovanna, Piroddi, Marta, Abdul, Hafiz Mohmmad, Sultana, Rukhsana, Galli, Francesco, Memo, Maurizio, Butterfield, D. Allan
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292396/
https://ncbi.nlm.nih.gov/pubmed/18077176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2007.11.004
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