Redox proteomics analysis of HNE-modified proteins in DS brain: clues for understanding development of Alzheimer disease

Down syndrome (DS) is the most common genetic cause of intellectual disability, due to partial or complete triplication of chromosome 21. DS subjects are characterized by a number of abnormalities including premature aging and development of Alzheimer’s disease (AD) neuropathology after approximatel...

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Bibliographic Details
Published in:Free Radic Biol Med
Main Authors: Di Domenico, Fabio, Pupo, Gilda, Tramutola, Antonella, Giorgi, Alessandra, Schininà, Maria Eugenia, Coccia, Raffaella, Head, Elizabeth, Butterfield, D. Allan, Perluigi, Marzia
Format: Artigo
Language:Inglês
Published: 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686229/
https://ncbi.nlm.nih.gov/pubmed/24675226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.03.027
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