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Catalytic asymmetric formal synthesis of beraprost

The first catalytic asymmetric synthesis of the key intermediate for beraprost has been achieved through an enantioselective intramolecular oxa-Michael reaction of an α,β-unsaturated amide mediated by a newly developed benzothiadiazine catalyst. The Weinreb amide moiety and bromo substituent of the...

詳細記述

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書誌詳細
出版年:Beilstein J Org Chem
主要な著者: Kobayashi, Yusuke, Kuramoto, Ryuta, Takemoto, Yoshiji
フォーマット: Artigo
言語:Inglês
出版事項: Beilstein-Institut 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685892/
https://ncbi.nlm.nih.gov/pubmed/26734111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.285
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