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Catalytic asymmetric formal synthesis of beraprost
The first catalytic asymmetric synthesis of the key intermediate for beraprost has been achieved through an enantioselective intramolecular oxa-Michael reaction of an α,β-unsaturated amide mediated by a newly developed benzothiadiazine catalyst. The Weinreb amide moiety and bromo substituent of the...
Shranjeno v:
| izdano v: | Beilstein J Org Chem |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Beilstein-Institut
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4685892/ https://ncbi.nlm.nih.gov/pubmed/26734111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.285 |
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